Late toxicity following craniospinal radiation for early-stage medulloblastoma
نویسندگان
چکیده
منابع مشابه
Late toxicity following craniospinal radiation for early-stage medulloblastoma.
BACKGROUND The purpose of this study is to review late toxicity following craniospinal radiation for early-stage medulloblastoma. MATERIAL AND METHODS Between 1963 and 2008, 53 children with stage M0 (n = 50) or M1 (n = 3) medulloblastoma were treated at our institution. The median age at diagnosis was 7.1 years (range 1.2-18.5). The median craniospinal irradiation (CSI) dose was 28.8 Gy (ran...
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A 16 year old girl who underwent surgery and radiotherapy for medulloblastoma is described. Shortly following the completion of treatment symptoms developed suggestive of tumour recurrence. At post mortem the cause was identified as disseminated aspergillosis with extensive cerebral involvement. The importance of this unusual complication is discussed.
متن کاملAcute toxicity profile of craniospinal irradiation with intensity-modulated radiation therapy in children with medulloblastoma: A prospective analysis
BACKGROUND To report on the acute toxicity in children with medulloblastoma undergoing intensity-modulated radiation therapy (IMRT) with daily intrafractionally modulated junctions. METHODS Newly diagnosed patients, aged 3-21, with standard-risk (SR) or high-risk (HR) medulloblastoma were eligible. A dose of 23.4 or 36.0 Gy in daily fractions of 1.8 Gy was prescribed to the craniospinal axis,...
متن کاملA review of dosimetric and toxicity modeling of proton versus photon craniospinal irradiation for pediatrics medulloblastoma.
BACKGROUND Craniospinal irradiation (CSI) is the standard radiation therapy treatment for medulloblastoma. Conventional CSI photon therapy (Photon-CSI) delivers significant dose to surrounding normal tissue (NT). Research into pediatric CSI with proton therapy (Proton-CSI) has increased, with the aim of exploiting the potential to reduce NT dose and associated post-treatment complications. This...
متن کاملRadiation : early warnings ; late effects
Since the discovery of ionising radiation just over 100 years ago, it has been appreciated that injudicious exposure could produce harmful effects, even death. However, the general excitement in the scientific community and the, often inappropriate, publicity which followed these discoveries ensured that the damage to health, particularly in the long term, was not given any prominence. The undo...
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ژورنال
عنوان ژورنال: Acta Oncologica
سال: 2014
ISSN: 0284-186X,1651-226X
DOI: 10.3109/0284186x.2013.862596